Wegovy vs Mounjaro: Which Weight Loss Injection is Best for you?

Wegovy vs Mounjaro - Which Weight Loss Injection Works Best in 2025

Medical weight loss injections have transformed the way we approach weight management. At Shape 8, two treatments come up most often in consultations are Wegovy and Mounjaro.

Both can deliver impressive results, but they work in different ways. This guide will help you understand the differences and decide which could be the right choice for your goals and lifestyle.

What is Wegovy?

Wegovy contains semaglutide a GLP-1 receptor against. It is taken once a week and works by:

Slowing digestion
Reducing appetite
Helping you feel full for longer

Who it's for: Adults with a BMI of 30 or higher, or 27+ with a weight-related health condition such as high blood pressure or type 2 diabetes.

Average results: Clinical studies show around 15% weight loss over 68 weeks when combined with healthy eating and regular exercise.

What is Mounjaro?

Mounjaro contains tirzepatide, which targets two hormones GLP-1 and GIP for a dual effect:

May lead to greater average weight loss than GLP-1 medication alone.
Improves blood sugar control
Suppresses appetite

Who it's for: Approved for type 2 diabetes but widely prescribed for weight loss.

Average results: Studies show 20%+ body loss over 72 weeks with lifestyle changes.

Wegovy vs Mounjaro at a Glance

Wegovy (Semaglutide)

Targets GLP-!! hormone only
Average weight loss around 15%
Approved specifically for weight loss
Side effects: nausea, constipation, diarrhoea
Usually more affordable than Mounjaro

Mounjaro (Tirzepatide)

Targets both GLP-1 and GIP hormones
Average weight loss: around 20%+
Approved for type 2 diabetes (used for weight loss)
Side effects similar to Wegovy, sometimes stronger gastrointestinal symptoms
Typically more expensive than Wegovy

Possible Side Effects

Both injections can cause:

Nausea or vomiting
Constipation or diarrhoea
Indigestion or bloating
Reduced appetite

Rare but serious risks include pancreatitis and gallbladder problems, Always start treatment under medical supervision.

Which is best for you?

Your choice will depend on:

Your weight loss target - Mounjaro may offer greater average results for some people
Your health history - Especially if you have type 2 diabetes
Your budget - Wegovy usually more affordable
Availability - Mounjaro's approval for weight loss varies by country

The Shape 8 Approach

At Shape 8, we provide: