Go back to blogs

Wegovy vs Mounjaro: Which Weight Loss Injection is Best for you?

By Dr Kamran Amjed MD -
Example Post 3 Image

Wegovy vs Mounjaro - Which Weight Loss Injection Works is Best for you?

Medical weight loss injections have transformed the way we approach weight management.  At Shape⁸, two treatments come up most often in consultations are Wegovy and Mounjaro.

Both can deliver impressive results, but they work in different ways.  This guide will help you understand the differences and decide which could be the right choice for your goals and lifestyle.

What is Wegovy?

Wegovy contains semaglutide a GLP-1 receptor against.  It is taken once a week and works by:

  • Slowing digestion
  • Reducing appetite
  • Helping you feel full for longer

Who it's for: Adults with a BMI of 30 or higher, or 27+ with a weight-related health condition such as high blood pressure or type 2 diabetes.

Average results:  Clinical studies show around 15% weight loss over 68 weeks when combined with healthy eating and regular exercise.

 

What is Mounjaro?

Mounjaro contains tirzepatide, which targets two hormones GLP-1 and GIP for a dual effect:

  • May lead to greater average weight loss than GLP-1 medication alone.
  • Improves blood sugar control
  • Suppresses appetite

Who it's for:  Approved for type 2 diabetes but widely prescribed for weight loss.

Average results:  Studies show 20%+ body  loss over 72 weeks with lifestyle changes.

 

Wegovy vs Mounjaro at a Glance

Wegovy (Semaglutide)

  • Targets GLP1 hormone only
  • Average weight loss around 25% in 72 weeks
  • Approved specifically for weight loss
  • Side effects: nausea, constipation, diarrhoea
  • Usually more affordable than Mounjaro
  • Suitable for women on oral contraceptives
  • Dosage strength 0.25mg, 0.5mg, 1mg, 1.7mg, 2.4mg

Mounjaro (Tirzepatide)

  • Targets both GLP-1 and GIP hormones
  • Average weight loss: around 20%+
  • Approved for type 2 diabetes (used for weight loss)
  • Side effects similar to Wegovy, sometimes stronger gastrointestinal symptoms
  • Typically more expensive than Wegovy
  • Dosage strength 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, 15mg

Possible Side Effects

Both injections can cause:

  • Nausea or vomiting
  • Constipation or diarrhoea
  • Indigestion or bloating
  • Reduced appetite

Rare but serious risks include pancreatitis and gallbladder problems, Always start treatment under medical supervision.

Which is best for you?

Your choice will depend on:

  • Your weight loss target - Mounjaro may offer greater average results for some people
  • Your health history - Especially if you have type 2 diabetes
  • Your budget - Wegovy usually more affordable
  • Availability - Mounjaro's approval for weight loss varies by country

The Shape⁸ Approach

At Shape⁸, we provide:

  • Medically supervised Wegovy and Mounjaro treatment plans
  • Personalised support from start to finish
  • Ongoing guidance on nutrition, exercise and healthy habits

 

https://www.shape8.com/assessment/6?c=3819 

You might be interested

Awesome island Thumbnail
Mandy Sandhu - 25th September 2026

Is an In-Person Consultation at our...

Online weight-management services are convenient, but for some people nothing replaces sitting down with a clinician face-to-face. We look at the benefits of an in-person weight loss consultation and why...
Read more
Awesome island Thumbnail
Mandy Sandhu - 25th September 2026

Retatrutide Explained: Why Is It Called...

Retatrutide is different from many existing medicines being researched for weight management because it acts on three hormone receptors. We explain what GLP-1, GIP and glucagon do and why scientists are...
Read more
Retatrutide information
Mandy Sandhu - 25th September 2026

Retatrutide UK: What Is Reta and What...

Retatrutide, sometimes called Reta online, is attracting significant interest in weight-management research. We explain what it is, how it works, what clinical trials have found and its current status...
Read more
Awesome island Thumbnail
Mandy Sandhu - 23rd September 2026

Foundayo: What You Need To Know About...

Heard about Foundayo and wondering what it actually is? We explain this daily prescription tablet in plain English, from how it works to possible side effects and the questions with asking before starting...
Read more
Awesome island Thumbnail
Mandy Sangha - 21st September 2026

Welcome to the Shape8 Weight Loss Clinic...

The Shape8 weight loss clinic gives you the chance to get real world clinical support during your weight loss journey. Find out about services at the clinic here.
Read more
Wegovy pill comparison
Mandy Sandhu, Co Founder, Shape⁸ - 30th July 2026

Wegovy Pill vs Wegovy Injection: Which...

After losing over four stone with GLP-1 medication, Mandy Sandhu shares her personal experience of living with PCOS, overcoming grief and comparing the Wegovy pill with the Wegovy injection to help others...
Read more