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FAQs
How does Wegovy® Work?
Wegovy® mimics the action of the natural hormone GLP-1, which regulates appetite and food intake. By acting on specific brain receptors, it helps you feel fuller for longer, reduces hunger, and decreases food cravings. This makes it easier to follow a calorie-controlled diet and maintain weight loss.
What are the proven benefits of Wegovy®?
Clinically proven weight loss – on average, participants lost around 15% of body weight in clinical trials over 68 weeks when combined with diet and exercise.
Sustained results – benefits maintained for up to two years in long-term studies.
Heart health protection – a 20% reduction in the risk of heart attack, stroke, or cardiovascular death in high-risk adults, as shown in the select trial.
Improved cardiometabolic health markers, including lower blood pressure, reduced waist circumference, and improved cholesterol profiles.What are the Wegovy® Dosing & Administration Instructions?
Starting dose: 0.25 mg once weekly for 4 weeks.
Gradual dose increase every 4 weeks (0.5 mg → 1.0 mg → 1.7 mg) until reaching the maintenance dose of 2.4 mg once weekly.
Delivered via the Wegovy® FlexTouch® pre-filled pen for self-injection into the abdomen, thigh, or upper arm.
Pens are stored refrigerated before opening and can be kept below 30°C for up to 6 weeks after first use.Who Should Not Use Wegovy®?
Wegovy is not suitable for:
People under 12 years of age
Pregnant or breastfeeding women
Anyone allergic to semaglutide or the listed ingredients
People using other GLP-1 receptor agonist medications
Possible Side Effects
Common side effects include nausea, vomiting, diarrhoea, constipation, and stomach pain, especially during dose escalation. These often lessen over time. Serious but rare side effects can include pancreatitis, gallstones, severe allergic reactions, or bowel obstruction. Always discuss potential risks with your prescriber.
Why Choose Wegovy® from Shape8
Private prescription service with full eligibility screening
Fast, discreet UK delivery
Ongoing medical support to help you achieve and maintain results
Guidance on healthy eating and activity plans tailored to your needsWhat are the Possible Side Effects of Wegovy®
Common side effects include nausea, vomiting, diarrhoea, constipation, and stomach pain, especially during dose escalation. These often lessen over time. Serious but rare side effects can include pancreatitis, gallstones, severe allergic reactions, or bowel obstruction. Always discuss potential risks with your prescriber.
What are the Expected Results & Timelines of Wegovy®?
Wegovy® works gradually, helping you achieve sustainable results rather than rapid, short-term loss. In clinical trials, patients lost on average around 15% of their starting body weight over 68 weeks when combined with a healthy diet and regular physical activity. Many people begin noticing changes in appetite and early weight loss within the first month, with steady progress as the weeks go by.
What’s in the Wegovy® Box?
- 1 pre-filled Wegovy® FlexTouch® pen (containing four weekly doses)
- 4 disposable needles
- Patient Information Leaflet with step-by-step instructions

* This image is for illustration purposees only and does not reflect the actual size of the pen.
Wegovy® or Mounjaro?
What happens if I miss a dose of Wegovy®?
If your next scheduled dose is more than 48 hours away, take the missed dose as soon as you remember.
If your next scheduled dose is less than 48 hours away, skip the missed dose and take your next injection on your usual scheduled day.
If it has been 14 days or more since your last dose, either take your next dose on your regular scheduled day or speak to your healthcare professional for advice on how to restart treatment.
How to care for your Wegovy® pen?
Do not drop the pen or allow it to hit hard surfaces.
Keep the pen away from liquids and do not expose it to water.
If you believe the pen may be damaged, do not use it or attempt to repair it. Dispose of it safely and use a new pen.
To reduce the risk of infection, keep the cap on until you are ready to inject. The pen will no longer be sterile if it is stored without the cap, if the cap has been removed and replaced, or if the cap is missing.
How do I use Wegovy®?
Wegovy® is taken once weekly using the FlexTouch® pen. Always read the Patient Information Leaflet before starting, and speak to your doctor, nurse or pharmacist if you are unsure how to inject correctly.
1. Get started- Check the name and dose on the pen to ensure it matches your prescribed strength (0.25 mg, 0.5 mg, 1 mg, 1.7 mg or 2.4 mg).
- If prescribed 7.2 mg weekly (three injections of 2.4 mg), ensure you have enough 2.4 mg pens available before starting.
- Remove the pen cap and check the solution through the viewing window. The liquid should be clear and colourless.
- Do not use the pen if the solution appears cloudy or discoloured.
2. Attach a new needle
- Always use a new needle for every injection.
- If taking 7.2 mg (three 2.4 mg injections), use a new needle for each injection.
- Do not use bent or damaged needles.
- Remove the paper tab, push the needle straight onto the pen and twist until secure.
- Remove the outer needle cap and keep it.
- Remove and safely dispose of the inner needle cap.
3. Check the flow (new pens only)
Only required before the first injection with each new pen.
- Turn the dose selector until the flow check symbol aligns with the dose pointer.
- Hold the pen upright with the needle pointing upwards.
- Press and hold the dose button until the counter returns to 0.
- A small drop should appear at the needle tip.
If no drop appears:- Repeat once more.
- If still no drop, change the needle and try again.
- Do not use the pen if a drop still does not appear.
4. Set the dose
- If prescribed 7.2 mg weekly (three injections), select 2.4 mg for each injection.
- Turn the dose selector until the dose counter stops and shows your prescribed dose.
- When the dose lines up with the dose pointer, it has been correctly selected.
- Do not set the dose by counting clicks.
5. Choose an injection site and inject
- Insert the needle into your skin, ensuring the dose counter is visible.
- Press and hold the dose button until the counter shows 0.
- Keep the needle in your skin and slowly count to six. The 0 must align with the dose pointer.
- Remove the needle from your skin.
- If there is slight bleeding, apply gentle pressure.
If prescribed 7.2 mg weekly (three 2.4 mg injections):- Use a new needle for each injection.
- If a new pen is required for the second or third injection, repeat steps 1–5.
- The three injections may be given in the same body area but must be at least 5 cm apart.
- Do not discard a pen until it is empty.
- Store partially used pens in the fridge with the needle removed.
- Ensure you have enough pens to complete your full dose before starting.
6. After injection
- Carefully guide the needle into the outer needle cap placed on a flat surface.
- Do not attempt to replace the inner needle cap.
- Once covered, firmly push the outer cap on and unscrew the needle.
- Dispose of the needle safely in a sharps container.
- Replace the pen cap after each use to protect the medication from light.
Does Wegovy® affect oral contraception?
Wegovy® is not expected to reduce the effectiveness of oral contraceptives.
There is no requirement in the Summary of Product Characteristics (SmPC) for women of childbearing age to switch to a non-oral contraceptive method while taking Wegovy®.
Can Wegovy® reduce Cardiovascular Risk?
20% relative risk reduction (1.5% ARR) in MACE*
Wegovy® is the only weight management medication also approved to reduce cardiovascular risk in adults living with overweight or obesity who have established cardiovascular disease, when used alongside a reduced-calorie diet and increased physical activity.
Cardiovascular benefit beyond weight loss
A pre-specified analysis of the SELECT trial found that the reduction in major adverse cardiovascular events (MACE) with Wegovy® was observed regardless of the amount of weight lost at week 20 (both under 5% and 5% or more).
This suggests that the cardiovascular benefits of Wegovy® may extend beyond weight reduction alone.
* Wegovy® N=8803, placebo N=8801; the patients did not have diabetes. p<0.001.
Why does Wegovy® pens come in different colours?
Wegovy® is available in five dose strengths: 0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg and 2.4 mg.
Each strength is supplied in a pre-filled pen with a distinct colour to help identify the correct dose.
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